SMARTSIL 1000/5000
Purified Silicone Oil for
Vitreoretinal Surgery
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Maximum interfacial tension and minimum interactions between tissues, cells and endo-tamponades media
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Optimal combination of specific gravity, refractive index and surface tension
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The choice of viscosity for a balance between easy injection and a stable temporary tamponade
Physico-chemical properties
Interfacial tension: ≥ 40 mNm-1 at 37°C
Density: 0.97
Viscosity: 1000/5000 cSt
Refractive index: 1.40
Volatility: < 1%
Polydispersity: < 2.8
Volume of oil: 10 ml
Syringe: 20 ml
Indications:
SmartSil 1000/5000 is used for prolonged tamponade after surgical treatment for severe retinal detachment (RD), especially:
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RD with proliferative vitreal retinopathy
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RD with diabetic retinopathy complications
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RD with giant tears
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Traumatic RD
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Secondary RD with viral retinitis
Purification
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Vacuum molecular distillation solvent free purification
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Potentially toxic low molecular weight oligomers (D4 to D20) extraction
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Residual volatile components extraction (water, ethanol, etc.)
Post-purification controls
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Gel permeation chromatography (GPC)
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Gaseous chromatography (GC)
Sterilization
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Silicone oils are dry heat sterilized
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Syringes are steam sterilized